Biochemistry analyzer

WHAT IS CHEMISTRY ANALYZER

Biochemistry analyzers compute the quantity or flow of certain proteins, enzymes, electrolytes, metabolites or even drugs in the provided samples of blood, urine, plasma serum and many body liquids. It has been used in small and medium-sized hospitals and test centers, as well as large hospitals, such as university hospitals, etc. The ultra small volume measurement function is expected to contribute to the development of test items, such as for immunity, tumor markers, drugs, infection markers, etc. as well as to the development of pharmaceutical products.

METHOD USED IN BIOCHEMISTRY ANALYZER

There are various methods of introducing samples into the analyzers.

Spectrophotometry method-

Photometry is the most common method for testing the amount of a specific analyte in a sample. In this technique, the sample undergoes a reaction to produce a color change. Then, a photometer measures the absorbance of the sample to indirectly measure the concentration of the analyst present in the sample.

Ion selective method-

The use of an Ion selective is another common analytical method that specifically measures Ion concentration. This typically measures the concentration of sodium, calcium or potassium present in the sample.

Ion Selective Electrode Measurement - Fundamentals in Online Analysis

DIGNOSING OF DISEASE

Perform test on whole blood, serum plasma or urine samples to determines concentration of analyte (e.g cholesterol, electrolytes, glucose, calcium) to provide certain hematology values and to assay certain therapeutic drugs which help diagnoses and treat numerous disease, including diabetes, cancer, HIV, STB, hepatitis, kidney conditions, and thyroid problems.

WHAT ARE THE APPLICATION OF CHEMISTRY ANALYZER

  • This tool helps doctors to identify important problems.
  • Scientists also use it to know how biomolecules work.
  • It is also used in drug investigations, advancing medical research, product development approaches and diagnostics.
  • This tool is considered important to perform the tasks very carefully.
  • These devices help in doing many important tests, so they are like the backbone of the biomedical department.

WHAT ARE THE COMPONENTS OF BIOCHEMISTRY ANALYZER

BA400 | New clinical chemistry and turbidimetry analyzer | Biosystems
  • Sampler
  • Proportioning pump unit
  • Dialyzer assembly
  • Constant temperature module
  • Flow through colorimeter
  • Recorder assembly

Sampler- in a chemistry analyzer pipette draw the sample fluids and deposits into another vial or container for mixing or analysis. Pressure sensors are used to ensure that the right amount of fluid is being measured while the sample is being drawn.

Proportioning pump unit- the metering pump is a positive displacement chemical dosing device is the ability to vary capacity or manually automatically process conditions required. It features a high level of repetitive accuracy and is capable of pumping a wide range of chemicals including acids, bases or viscous liquids and slurries.

Dialyzer assembly- these modules achieve the separation of small and large molecules by allowing the former to pass through a semipermeable membrane from the donor stream of liquids and air bubble to a recipient stream of liquids again segmented by air bubbles.

Constant temperature module- The temperature change measured by the calorimeters is used to derive the amount of heat transferring the process under study.

Flow through colorimeter- This process involves adding a chemical reagent to a water sample to be measured. Because the color absorption is proportional dependent upon the chemical substances found with the sample.

Recorder assembly- 10 MS dynamic cuvette blank reading in the same way reactions are read.

WHAT ARE THE OPERATIONS USED IN CHEMISTRY ANALYZER

HOW DOES THE WORK CHEMISTRY ANALYSERS

Samples are inserted in the slot or loaded onto a tray, and tests are programmed via a keypad or bar code scanner. Reagents may be stored with the analyzer, and it may require a water supply to wash internal parts. Results are displayed on screen, and typically there are ports to connect to a printer or computer.

After the tray is loaded with sample, a pipette aspirates a precisely measured aliquot of sample and discharges it into the reaction vessel; a measured volume of diluent rinses the pipette. Reagents are dispensed into reaction vessels.

After the solution is mixed, it is either passed through a colorimeter, whose measurement is observance while it is still in its reaction vessel, or aspirated into a flow cell, where it’s observance is measured by a flow through colorimeter.

WHAT ARE THE TYPES OF BIOCHEMISTRY ANALYZER

There are major types of Biochemistry analyzer:

SEMI-AUTO CHEMISTRY ANALYZER

Semi-Auto Chemistry Analyzer, Clinical Chemistry Analyzers, रसायन विश्लेषक in Dahisar West, Mumbai , Aditi Associate | ID: 4152613248

It is called semi because the initial stages of samples analysis is done by laboratory technicians. Its analyzers work based on two measurement methods: optical techniques and electrochemical techniques. The working is similar to that of the Fully Automated Biochemistry Analyzers. The main difference is that Semi-Automatic analyzers are more practical for use in smaller laboratories and medical practices. This is due to it being able to handle a lower number of samples at a time as compared to the fully automatic one.

FEATURES-

  • Flow cell and cuvette modes must be there to ensure all types of tests can be done.
  • Onboard reaction curve to monitor results for different parameters.
  • Multiple filters for different applications
  • Simple user interface for ease of use
  • Auto-save functionality for measurements in the case of power-off

PROS AND CONS OF SEMI-AUTO ANALYZER

Pros

  • display the test results
  • printing and memorizing these results
  • graph of all reaction

Cons

  • initial stage of analysis are performed manually: pipetting of reagent, pipetting of specimen.

TOP 3 SEMI AUTO CHEMISTRY ANALYZERS

1.

Erba Semi Automatic Chem 5x Biochemistry Analyzer

  • This biochemistry analyser is a premium quality best biochemistry machine. This auto analyser is manufactured by using quality assured material and advanced techniques, which make them up to the standard in this highly challenging field. You can use this fully automatic biochemistry analyzer in labs. The materials utilized to manufacture this biochemistry test machine are sourced from the most reliable and official vendors, chosen after performing detailed market surveys. Erba products are widely acknowledged in the market for their high quality. We are dedicatedly involved in providing an excellent quality array of Erba biochemistry analyzer.

  • PRODUCT SPECEFICATION
Storage1000 Test patient results storage
Wavelength340, 405, 505, 546, 578, 630 n.m.
Photometric Range0 to 3.0 OD
Static Photometer340-630 n.m.
USB SupportYes
  • PRODUCT FEATURES
  • Extensive Biochemistry test menu
  • Elaborate Q.C. Program memory
  • Inbuilt printer
  • Graphic Display
  • 1000 test Result storage
2.

Erba Chem 7 Transasia Biochemistry Analyzer – Semi Automatic

  • This biochemistry analyser is a premium quality best biochemistry machine. This auto analyser is manufactured by using quality assured material and advanced techniques, which make them up to the standard in this highly challenging field. You can use this fully automatic biochemistry analyzer in labs. The materials utilized to manufacture this biochemistry test machine are sourced from the most reliable and official vendors, chosen after performing detailed market surveys. Erba products are widely acknowledged in the market for their high quality. We are dedicatedly involved in providing an excellent quality array of Erba biochemistry analyzer.

  • PRODUCT SPECEFICATION
Power Supply 70 W
Voltage18V DC,115/230V AC (+- 10%)
Keyboard41 Multifunction Keys and 6 dynamic keys
PrinterIn-Built High-Resolution Graphic Thermal Printer
Optional AccessoriesExternal 16 Position Dry Block Incubator
  • Product Features:
  • 56 Direct Access Keys
  • Monitoring of Q.C.
  • Online Display of Reaction Curve
  • Unique Triple Cuvette System
  • Low Reagent Consumption
  • Direct Printer / Keyboard Connectivity
3.

Mindray BA 88A Biochemistry Analyzer – Semi Auto

  • This biochemistry analyser is a premium quality best biochemistry machine. This autoanalyser is manufactured by using quality assured material and advanced techniques, which make them up to the standard in this highly challenging field. You can use this fully automatic biochemistry analyzer in labs. The materials utilized to manufacture this biochemistry test machine are sourced from the most reliable and official vendors, chosen after performing detailed market surveys. Mindray products are widely acknowledged in the market for their high quality. We are dedicatedly involved in providing an excellent quality array of Mindray biochemistry analyzers.

  • PRODUCT SPECEFICATION
touch scree7.0- TFT
External keyboard yes
support via USByes
Wavelengths range340 to 670nm 8 Filter 
tests can be programmedUp to 200 
  • PRODUCT FEATURES
  • Endpoint, Fixed-time, Kinetics and Absorbance
  • Test mode: flowcell or cuvette
  • User-friendly interface
  • Power-failure protection
  • Universal power supply
  • Power Failure Protection
  • Semi-Automatic Chemistry Analyser

FULL AUTOMATED CHEMISTRY ANALYZER

Mindray Fully Automatic Clinical Chemistry Analyzer, | ID: 19179450430

It is designed to measure biochemical parameters quickly, with minimal human assistance. Automatic dispensing of reagents (reagent probe), sample (samples probe), mixing, incubating etc.

FEATURES-

  • Sampler to accommodate sample, standard, calibrator.
  • Programmable probes sample- sample volume 3 to 30.
  • Samples and reagent probes have sensors.
  • Reusable reaction cells.
  • Programmable wash cycles.
  • Cuvette rising stations clean with detergent and deionized water- to provide precise and reliable results.

PROS AND CONS OF SEMI-AUTO ANALYZER

Pros

  • high stability regent
  • absence of toxicity
  • mainly used for analysis test

Cons

  • more man power require
  • reagent waste
  • maintenance cost high

TOP 3 FULLY AUTOMATED CHEMISTRY ANALYZER

1.

Mindray BS 240 Biochemistry Analyzer

  • BS-240 is a “CUTE”, multi-functional benchtop clinical chemistry analyzer with a throughput at 200 T/H.
  • Though with a compact size, it has achieved a host of advanced functions never before found on a like product in the market, making it an optimal chemistry solution for small laboratories and a back-up tool for mid-to-high end laboratories.

  • PRODUCT SPECIFICATIONS
ModelBS-240
Usage Pathology Lab
Power Supply 220 Volt
Poeration ModeFully automated
  • PRODUCT FEATURES
  • 40 positions for sample and 40 positions for reagent, 40 interchangeable to extend.
  • Step-by-step maintenance guide for easy operation
  • Smart-sampling technology enables automatic
  • A minimum of 100μl reaction volume for reagent saving.
2.

Mindray BS-230 Biochemistry Analyzer – Fully Automatic

  • This biochemistry analyser is a premium quality best biochemistry machine. This autoanalyser is manufactured by using quality assured material and advanced techniques, which make them up to the standard in this highly challenging field. You can use this fully automatic biochemistry analyzer in labs.
  • The materials utilized to manufacture this biochemistry test machine are sourced from the most reliable and official vendors, chosen after performing detailed market surveys.
  • Mindray products are widely acknowledged in the market for their high quality. We are dedicatedly involved in providing an excellent quality array of Mindary biochemistry analyzers.

  • PRODUCT SPECIFICATION
AutomationFully Automatic
Model Number/NameBS -230
ParametersClinical Chemistry
AssaysClinical Chemistry
Type Of SystemOpen
  • PRODUCT FEATURES
  • Flexible loading
  • 100μl minimum reaction volume
  • Disposable Cuvettes to avoid contaminatio
  • Probe carryover less than 0.05%
3.

Erba EM200 Fully Automated Biochemistry Analyzer, For Clinical

  • EM 200 is a fully automated, random access and discrete clinical chemistry analyzer that enhances productivity and turnaround time. It has a throughput of 200 photometric tests per hour and 400 tests/hr. with ISE (Optional). EM 200 is fast and an accurate chemistry analyzer that has been designed for growing and mid-size laboratories. EM 200 can comfortably handle the demands of an increased workload in a convenient and cost efficient way. It adds value to the laboratory and is an ideal choice for Mid-size labs. 

  • PRODUCT SPECIFICATIONS
Reading Volume180 Micloliter
Power Consumption600 VA
Sample TypeWhole Blood, Serum, Plasma, Urine, CSF Other
Dimension810 x 800 x 600 mm (W x D x H)
Throughput200 Photometric Tests/Hour & 400 Tests/Hour With ISE (Optional)
  • PRODUCT FEATURES
  • Flexibility for STAT samples at any point of time
  • Real time monitoring of reaction curves
  • Unlimited data storage capacity
  • Windows Xp based user friendly software
  • Multiple calculation modes such as linear, non-linear & multipoint.

PRECAUSTIONS FOR THE USERS

  • Operators should be aware of the risks for exposure to potentially infectious blood borne pathogens during testing procedure and should use universal precautions, including wearing gloves, face shield or masks, and gowns.
  • Maintenance is done by laboratory technicians, biomedical or clinical engineers and the initial training from manufacturer and manual is necessary.

FUTURE OF CHEMISTRY ANALYZER

Advances in clinical chemistry analyzers will be concurrent with the development of new assays, further improving patient care. Manufacturers are customizing analyzers for use in smaller laboratories, use in very high volume situations such as in a large hospital, or in the field. As software capabilities continue to develop, clinical chemistry analyzers will be able to offer increased testing speed and degree of automation.

FREQUENTLY ASKED QUESTIONS (FAQs)

What is the principle of chemistry analyzer?

It converts the quantity of a specific substance in blood into an amount of color change for measurement.

What are automated chemical analyzers?

An automated analyzer is a medical laboratory instrument designed to measure different chemicals and other characteristics in a number of biological samples quickly, with minimal human assistance. 

Why biochemistry test is done?

Biochemical tests are most often applied to samples of serum, plasma and urine where levels of specific chemicals are measured and the results compared with those representative of a healthy individual.

What is analyzer System?

Process Analyzer System is a facility to measure necessary parameters such as hydrocarbons to help optimize the manufacturing process

How do I choose a biochemistry analyzer?

When choosing a biochemistry analyzer it is important to take into account whether assay automation is required, the specificity of the reagents and the level of accuracy of the measurements.

Is biochemistry a urine test?

Assessment of Urine Biochemistry

Urine biochemistry can provide important ancillary diagnostic information. This chapter summarizes the common uses of urine biochemistry in the intensive care unit (ICU) and how they may aid in the diagnosis, investigation, and monitoring in a variety of conditions.

How many tests are there in biochemistry?

The lab’s efficient systems enable routine testing for more than 30 different tests using only a single tube of blood.

CONCLUSION

The Clinical Biochemistry Analyzer is an instrument that uses the pale yellow supernatant portion (serum) of centrifuged blood sample or a urine sample, and induces reactions using reagents to measure various components, such as sugar, cholesterol, protein, enzyme, etc. These tests are performed for routine health checks or at hospitals, and the results provide objective data enabling early detection and diagnosis of disease, as well as indicating the effects of treatment and patient prognosis.